In the paper there are described directions of distributed and high performance computing (HPC) technologies integration. Analysis of trends in the development of computer technologies, which focused on creating conditions for solving complex problems with high demands of computing resources is presented. The result of these studies is the following conclusion: the main development directions focused on integration of distributed Grid and parallel HPC facilities on the base of virtualization paradigm within integrated Cloud infrastructure in order to expand the range of opportunities for end-users by providing heterogeneous computing resources. Perspectives of utilization of Cloud technologies for integration of Grid and HPC clusters in heterogeneous computer infrastructures that are offering effective resources and end-user interfaces are considered.