The mixinvasions with ectoparasites (malophagous, fleas and gamasid acarians) provoke in the organism of the infected chickens at the initial stage the significant increasing of leukocytes (86,3%), granulocytes (30,2%), which indicates the existence of acute phase of inflammatory process of muscular tissue and internal organs and a state of accentuated swelling. The essential increasing of eosinocytes (by 1,2-1,5 times) in hens with poliparatism represent an important marker of these parasitoses evolution. The use of antiparasite treatment with preparations of vegetal origin Ectostop T 5% and Ectostop P 5% lead to the decreasing of leukocyte number, which, probably, indicate toward the harmless of tested preparations and high resistance of the organism, while the increasing of lymphocyte and monocyte level could be considered as positive, because it indicate the cellular protection status of the organism and can serve as benefic index of physiological status of the organism.