Role of cyclodextrins in new antimycobacterial formulations
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Chimie organică (484)
Farmacologie. Terapeutică. Toxicologie (1592)
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BOLDESCU, Veaceslav, MAKAEV, Fliur, DUKA, Gh.. Role of cyclodextrins in new antimycobacterial formulations. In: Chemistry Journal of Moldova, 2014, nr. 1(9), pp. 8-13. ISSN 1857-1727. DOI: https://doi.org/10.19261/cjm.2014.09(1).01
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Chemistry Journal of Moldova
Numărul 1(9) / 2014 / ISSN 1857-1727 /ISSNe 2345-1688

Role of cyclodextrins in new antimycobacterial formulations
DOI:https://doi.org/10.19261/cjm.2014.09(1).01
CZU: [547.458.68+547.917]:615.014.2

Pag. 8-13

Boldescu Veaceslav, Makaev Fliur, Duka Gh.
 
Institute of Chemistry of the Academy of Sciences of Moldova
 
 
Disponibil în IBN: 17 iulie 2014


Rezumat

This paper is dedicated to the role of cyclodextrins in new formulations for the treatment of infections with Mycobacterium tuberculosis that are in the process of design and development. Cyclodextrins play the role of solubilizing agents and promoters of the antimycobacterial substances penetration inside the mycobacterial cell. Different formulations and their advantages and disadvantages are discussed.

Cuvinte-cheie
cyclodextrin, tuberculosis, cholesterol, nano-encapsulation, mycobecteria