Internal migration is one of the main demographic processes that determine changes in the population structure in the districts of Moldova. The intensity of internal migration is determined by multiple social and economic factors and the migratory potential of the regions of migrants’ origin. This study analyses internal migration in Moldova at the district level using the National Bureau of Statistics data on permanent residence changes. The results show that the internal migration flows are dominated by the young and working-age population between the age of 15-50, who are mainly involved in rural-urban migration. Among the overall number of internal migrants, females exceed males, which creates a disparity in the sex ratio at certain ages in certain localities. Internal migrants are primarily attracted by the main cities, such as Chisinau and Balti, and by the districts in the vicinity of the capital city. As a result, the population increase in these cities is mainly due to internal migration.