The geodemographic component plays an essential role in territorial socio-economic development. The river basin of Răut on its lower segment (as part of a detailed study within an institutional project) is not an exception in this respect; the human dimension has the role of an important actor in the environment, but also a beneficiary of programs, projects, strategies of territorial development. The local, zonal, underregional level is the starting point for a complex system of interrelations, which will diversify to the higher regional and state levels. This detailing provides a better understanding of human evolution as well as the deduction of trends that are shaped in a territorial zonal profile. This study includes an assessment of the geodemographic component at the level of the primary territorial-administrative units and could serve as a reference for substantiating sectoral and territorial development policies.