The aim of this communication is to argue that spectral collocation based on Laguerre (LGRC), Hermite (HC) as well as Sinc (SiC) functions o ers reliable and accurate solutions to a large class of eigenvalue problems on unbounded domains. We consider non-standard eigenvalue problems, singular and/or self-adjoint as well as eigenproblems supplied with boundary conditions depending on eigenparameter ([2]). Recently we have obtained important results concerning eigenvalue problems with transmission conditions. In order to estimate the accuracy of outcomes we display the behavior (the decreasing way) of the expansion coecients of solutions. Because this method works in physical space, to get these coecients in the spectral space we make use of the FFT or another polynomial transforms ([1]). To the same aim we compute the relative drift of a speci ed set of eigenvalues. The orthogonality of eigenvectors is another way we asses the accuracy of our computations. The communication will be illustrated with a large number of gures and tables. They underline the eciency of spectral collocation methods used to solve eigenproblems on unbounded domains.