Computational issues regarding the parameter sensitivity in biological models
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2023-03-03 15:13
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DIMITRIU, Gabriel. Computational issues regarding the parameter sensitivity in biological models. In: Conference on Applied and Industrial Mathematics: CAIM 2018, 20-22 septembrie 2018, Iași, România. Chișinău, Republica Moldova: Casa Editorial-Poligrafică „Bons Offices”, 2018, Ediţia a 26-a, p. 47. ISBN 978-9975-76-247-2.
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Conference on Applied and Industrial Mathematics
Ediţia a 26-a, 2018
Conferința "Conference on Applied and Industrial Mathematics"
Iași, România, Romania, 20-22 septembrie 2018

Computational issues regarding the parameter sensitivity in biological models


Pag. 47-47

Dimitriu Gabriel
 
University of Medicine and Pharmacy “Grigore T. Popa”, Iasi
 
Disponibil în IBN: 31 mai 2022


Rezumat

The aim of this talk is to present computational issues contained in parameter sensitivity studies associated to several biological models. The local sensitivity is carried out by using the QR decomposition with column pivoting to the relative sensitivity matrix. We evaluate the relative identi ability of the parameters and establish orderings with respect to their identi ability. Also, a global sensitivity analysis is performed with sensitivity heat maps of the model variables and parameter sensitivity spectra.