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SM ISO690:2012 GULEAC, Natalia, HADJIU, Svetlana. Neonatal meningitis: etiology and clinical manifestations. In: Cercetarea în biomedicină și sănătate: calitate, excelență și performanță, Ed. 1, 20-22 octombrie 2021, Chişinău. Chișinău, Republica Moldova: 2021, p. 376. ISBN 978-9975-82-223-7 (PDF).. |
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Cercetarea în biomedicină și sănătate: calitate, excelență și performanță 2021 | ||||||
Conferința "Cercetarea în biomedicină și sănătate: calitate, excelență și performanță" 1, Chişinău, Moldova, 20-22 octombrie 2021 | ||||||
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Pag. 376-376 | ||||||
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Rezumat | ||||||
Background. Neonatal meningitis is an inflammatory condition of the meninges, with severe evolutionary potential, caused by the differentiation of infectious agents manifested in the first 28 days of life, which is a major clinical problem with a high risk of morbidity and mortality among newborns. Objective of the study. Estimating the type and etiology of meningitis in newborns for the purpose of analyzing treatment to improve early and distant neurological outcomes. Material and Methods. We evaluated 12 medical records of newborns (7 b, 5 g) aged 0-28 days, who were treated in the neurology department of the newborn of IMC during years 2018-2019. The clinical manifestations, the results of the laboratory examinations were evaluated: clinical, biochemical, bacteriological, as well as the imaging ones. The SPSS program was used for statistical analysis. Results. Neonatal meningitis with early onset - 41.7%; late onset - 58.3%; primary - 33.3%; secondary - 66.7%; causes: (1) bacterial - 41.7%: Streptococcus B (40%), Escherichia Coli (20%), Klebsiella (20%); viral - 50%: Herpes virus type I (50%), Cytomegalovirus (33.3%), Enteroviruses (16.7%); fungal - 8.3% (Cryptococcus neoformans). Symptoms in meningitis with early onset: temperature instability, episodes of apnea or bradycardia, hypotension, eating difficulties, liver dysfunction, abdominal distension, irritability or lethargy; in the late onset: stupor and / or irritability, convulsions, bulging of the anterior fontanelle, opisthotonos, focal cerebral signs. Conclusion. Neonatal meningitis is a high risk of mortality among newborns and morbidity, causing severe neurological sequelae. Early diagnosis of neonatal meningitis but also etiological is essential in terms of early treatment and subsequent prognosis of distant neurological outcomes. |
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Cuvinte-cheie Earlyneonatalmeningitis, lateneonatalmeningitis, cerebrospinalflu, meningita neonatală precoce, neonatală tardivă, lichid cefalorahidian |
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