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Ultima descărcare din IBN: 2024-03-05 16:01 |
SM ISO690:2012 GLOBA, Mihai, STEPCO, Elena. Abnormal oral phenotypes as a risk factor for cancer: hypodontia and ovarian cancer. In: Cercetarea în biomedicină și sănătate: calitate, excelență și performanță, Ed. 1, 20-22 octombrie 2021, Chişinău. Chișinău, Republica Moldova: 2021, p. 484. ISBN 978-9975-82-223-7 (PDF).. |
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Cercetarea în biomedicină și sănătate: calitate, excelență și performanță 2021 | ||||||
Conferința "Cercetarea în biomedicină și sănătate: calitate, excelență și performanță" 1, Chişinău, Moldova, 20-22 octombrie 2021 | ||||||
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Background. Hypodontia is one of the most common defects in tooth development in humans. Numerous studies have shown an association between the genetic determinants of hypodontia and neoplasms in adults. Ovarian cancer is a fatal condition that is detected late. Objective of the study. Synthesis of data from the literature to identify a potential prognostic relationship between hypodontia and ovarian cancer. Material and Methods. The research is based on the analysis of publications from the scientific databases of the national and international library, period 2014-2021. All studies that reported data on the presence of ovarian cancer and hypodontia were included in this review. The publications were searched in the online databases PubMed, Google Scholar, SCOPUS, Hinari and Sci-hub. Results. Based on data from the current literature, hypodontia was diagnosed in 19.3% of ovarian cancer patients compared to the control group 6.7%. Thus, patients with ovarian cancer (depending on the study) are 3.3 or 8.1 times more likely to have hypodontia than healthy women. Hypodontia is also more common in patients with bilateral ovarian cancer. No specific genes responsible for the coexistence of these two pathological entities were found. Conclusion. Preliminary data suggest a possible correlation between hypodontia and ovarian cancer. Thus, hypodontia could become a risk marker for the development of ovarian cancer. |
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Cuvinte-cheie hypodontia, ovarian cancer, dental agenesis, odontogenesis, carcinogen, hipodonția, cancerul ovarian, agenezia dentară, odontogeneză, cancerogen |
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