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SM ISO690:2012 POGORNILA, Elena, COJOCARU-TOMA, Maria. Phytotherapeutic products containin galk aloids according to the state nomenclature of medicines of the Republic of Moldova. In: Cercetarea în biomedicină și sănătate: calitate, excelență și performanță, Ed. 1, 20-22 octombrie 2021, Chişinău. Chișinău, Republica Moldova: 2021, p. 452. ISBN 978-9975-82-223-7 (PDF).. |
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Cercetarea în biomedicină și sănătate: calitate, excelență și performanță 2021 | ||||||
Conferința "Cercetarea în biomedicină și sănătate: calitate, excelență și performanță" 1, Chişinău, Moldova, 20-22 octombrie 2021 | ||||||
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Pag. 452-452 | ||||||
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Background. Alkaloids are nitrogenous heterocyclic organic substances of plant origin, which in defined doses have a pronounced pharmacodynamic action, and in high doses are toxic. Pyrrolizidine, isoquinoline, indole and acyclic alkaloids are more often found in the phytotherapeutic products. Objective of the study. Evaluation of phytotherapeutic products containing alkaloids according to the chemical classification, pharmaceutical forms, and to the State Nomenclature of Medicines of the Republic of Moldova. Material and Methods. It was evaluated the profile literature on phytotherapeutic products containing alkaloids. Phytotherapeutic products and their pharmaceutical forms with alkaloids, according to the State Nomenclature of Medicines of the Republic of Moldova, served as objects study. Results. Phytotherapeutic products containing alkaloids (190) account for 3.4% after Nomencaltor, with a diverse range of medicinal forms: tablets 45%, oral solutions 27%, injectable solutions 12%, vegetal products and medicinal species of 1,6% each. Homeopathic products with low risk of toxicity hold 11.2%, mostly with anti-inflammatory action (Discus Compositum, Guna Flam, Arnica-Heel); analgesic (Tonsilotren, Dentokind); regenerators (Guna Dermo, Aflubin); hepatoprotective (Hepar compositum, Hepeel); venotonizing (Aesculus compositum, Guna Anti-Age Vein); hypnotic (Guna Dizzy) and expectorant (Bronchalis Heel). Conclusions. Phytotherapeutic products containing alkaloids, in the pure state and semi-synthetic derivatives, share for 3.4% compared to the total number of authorized products and included in the State Nomenclature of Medicines of the R. of Moldova, of which 45% are in the form of tablets. |
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Cuvinte-cheie alcaloids, phytotherapeutic products, alcaloizi, produsele fitoterapeutice |
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