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SM ISO690:2012 ALEXA, Zinaida, MORARI, Vera, CEBOTARI, Inga, TERENTI, Feodora, DARII, Felicia, GULCANEAN, Anna. Dysglycemia and COVID-19. In: Cercetarea în biomedicină și sănătate: calitate, excelență și performanță, Ed. 1, 20-22 octombrie 2021, Chişinău. Chișinău, Republica Moldova: 2021, p. 196. ISBN 978-9975-82-223-7 (PDF).. |
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Cercetarea în biomedicină și sănătate: calitate, excelență și performanță 2021 | |||||
Conferința "Cercetarea în biomedicină și sănătate: calitate, excelență și performanță" 1, Chişinău, Moldova, 20-22 octombrie 2021 | |||||
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Rezumat | |||||
Background. SARS-CoV-2 infection contributes to the development of extrapulmonary manifestations such as diabetes mellitus and stress hyperglycemia, both of which have poor prognosis, higher rate of complications and increased risk of mortality. Objective of the study. The aim of the study was to evaluate the rate of people with different degree of dysglycemia among hospitalized patients with confirmed COVID-19. Material and Methods. The study is retrospective. We analyzed fasting blood glucose in 1791 patients with severe forms of COVID-19 during their hospitalization period and treatment of SARS-CoV-2 infection. HbA1c was evaluated at people with high fasting blood glucose levels to reveal the pre-existing diabetes. Results. The mean age of the patients included in the study was 57.72 ± 12.34 years, the mean value of BMI was 30.54 ± 5.51 kg / m2, the average level of fasting blood glucose value was 8.66 ± 4.45 mmol/l and HbA1c - 7.2 ± 1.94%. According to anamnestic data at admission 22% of patients knew about their diabetes. Blood glucose analysis during hospitalization showed that only 28% of patients had blood glucose levels within normal values. Analyzing the level of fasting blood glucose and HbA1c, primary diabetes was diagnosed in 7% of patients, prediabetes in 15% and 28% of patients had solitary changes in fasting blood glucose. Conclusion. To conclude, SARS-CoV-2 infection predisposes to appearance of dysglycemia in patients with severe forms of COVID-19, especially in people with risk factors for the development of diabetes (age, obesity, cardiovascular disease etc.) and those who have administered glucocorticoid treatment. |
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Cuvinte-cheie diabetes mellitus, prediabetes, fasting blood glucose, COVID-19, COVID-19, glicemia a jeun, diabet zaharat, prediabet |
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