Articolul precedent |
Articolul urmator |
329 1 |
Ultima descărcare din IBN: 2024-03-20 20:00 |
SM ISO690:2012 SADOVICI-BOBEICA, Victoria, SARMANIOTOU, Iliana, GARABAJIU (PAȘALÎ), Maria, MAZUR-NICORICI, Lucia, MAZUR, Minodora. Thyroid autoimmune involvment in patients with SLE. In: Cercetarea în biomedicină și sănătate: calitate, excelență și performanță, Ed. 1, 20-22 octombrie 2021, Chişinău. Chișinău, Republica Moldova: 2021, p. 142. ISBN 978-9975-82-223-7 (PDF).. |
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Cercetarea în biomedicină și sănătate: calitate, excelență și performanță 2021 | ||||||
Conferința "Cercetarea în biomedicină și sănătate: calitate, excelență și performanță" 1, Chişinău, Moldova, 20-22 octombrie 2021 | ||||||
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Background. Systemic lupus erythematosus (SLE) is a polysyndromic autoimmune disease of unknown etiology. Lupus manifestations include the involvement of several systems, including the endocrine system. Objective of the study. The article describes the association of systemic lupus erythematosus and autoimmune thyroid disease, it’s incidence and prevalence, pathophysiological mechanisms, clinical manifestations and predictive factors. Material and Methods. All relevant literature was retrieved from PubMed, Oxford academic, Springer link, Science direct, NCBI and Research Gate restricted to the English language. The search strategies contained subject headings and keywords for ‘lupus’, ‘SLE’ or ‘systemic lupus erythematosus’, combined with “thyroid”, “autoimmune thyroiditis”. Results. Thyroid disorders are frequent in SLE and are multifactorial with a definite higher prevalence of hypothyroidism as well as thyroid autoantibodies, the data ranging from 4,4% to 24%, depending on the year of the study and characteristic of the cohorts. According to recent research, the function of the thyroid gland in SLE patients interfere with certain indices as patient’s age, use of immunosuppressive drugs and disease activity. Hyperthyroidism was described in a variety of cases in SLE patients, ranging from 0% to 6,5%. A limited number of cases of Graves' disease have been also reported in SLE patients, in agreement with the higher prevalence of thyroid autoimmunity. Conclusion. There is a frequent association of these diseases and due to nonspecific clinical picture in patients with SLE, physicians should be alert for early detection of possible lupus and thyroid disease. |
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Cuvinte-cheie systemic lupus erythematosus, thyroid, Autoimmune, cheie: lupus eritematos sistemic, tiroidă, autoimun |
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