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SM ISO690:2012 CAIPAC, Alina, PASCAL, Rodica, GUTU, Biatricia, GUTU, Biatricia, ROTARU, Larisa. Clinical importance of kidney biopsy and immunohistochemical examination. In: Cercetarea în biomedicină și sănătate: calitate, excelență și performanță, Ed. 1, 20-22 octombrie 2021, Chişinău. Chișinău, Republica Moldova: 2021, p. 117. ISBN 978-9975-82-223-7 (PDF).. |
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Cercetarea în biomedicină și sănătate: calitate, excelență și performanță 2021 | ||||||
Conferința "Cercetarea în biomedicină și sănătate: calitate, excelență și performanță" 1, Chişinău, Moldova, 20-22 octombrie 2021 | ||||||
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Pag. 117-117 | ||||||
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Background. Currently, renal biopsy is a key diagnostic tool in nephrological practice. By renal biopsy, nephrologists identified renal histological changes to establish the correct diagnosis of clinical- pathological entity and to approve the therapeutic plan. Objective of the study. Large-scale implementation of contemporary technologies by immunohistochemistry in clinical-paraclinical research of renal tissue. Material and Methods. Between March 2021 and May 2021, 6 renal biopsies were performed on patients in the Nephrology Department of the IMSP SCR “Timofei Moșneaga”. Renal biopsy puncture was guided by ultrasonography. Renal tissue collection was performed by percutaneous biopsy. Bioptic fragments were evaluated by the immunohistochemical method. The research continues to this day. Results. The following morphological changes were established: 1 patient (16,5%) with segmental focal glomerulosclerosis, 1 patient (16,5%) with type I membranoproliferative glomerulonephritis, 2 patients (33,5%) with membranous glomerulonephritis, 2 patients (33,5%) with renal amyloidosis. Conclusion. The perspective of histopathological and immunohistochemical examinations would provide an current image of kidney disease, which can serve as a useful resource for health policy decisions with implementation of specific therapeutic methods,which reduces the rate of chronic kidney disease |
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Cuvinte-cheie renal biopsy, histopathology, immunohistochemistry, biopsie renală, histopatologie, imunohistochimie |
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