Articolul precedent |
Articolul urmator |
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Ultima descărcare din IBN: 2024-03-12 23:20 |
SM ISO690:2012 FRUNZE, Valeria, DESEATNICOVA, Elena. Thyroid gland pathology in rheumatoid arthritis. In: Cercetarea în biomedicină și sănătate: calitate, excelență și performanță, Ed. 1, 20-22 octombrie 2021, Chişinău. Chișinău, Republica Moldova: 2021, p. 115. ISBN 978-9975-82-223-7 (PDF).. |
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Cercetarea în biomedicină și sănătate: calitate, excelență și performanță 2021 | ||||||
Conferința "Cercetarea în biomedicină și sănătate: calitate, excelență și performanță" 1, Chişinău, Moldova, 20-22 octombrie 2021 | ||||||
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Background. Rheumatoid arthritis is an autoimmune disease. The increased occurrence of thyroid dysfunction in rheumatoid arthritis patients has been reported in the literature. Some studies have confirmed an increased prevalence of rheumatoid arthritis in patients with autoimmune thyroid pathology. Objective of the study. To study the presence of thyroid gland (TG) pathology in patients with rheumatoid arthritis (RA) and to determine its correlation with disease activity. Material and Methods. A total of 59 rheumatoid arthritis and 48 non-RA patients were included in the study. Laboratory investigation included rheumatoid factor (RF), anti-CCP, CRP, ESR, TSH, fT4, TgAb, TPOAb. Disease activity in RA measured with DAS-28-ESR. Results. In patient with RA clinical hypothyroidism was reported in 20.33%, while 3.38% had clinical hyperthyroidism. Subclinical hyperthyroidism was reported in 11.86% of the RA patients, while 3.38% had subclinical hypothyroidism. In control group, subclinical hyperthyroidism was reported in 4,16 % of the patients, 2.08% had clinical and subclinical hypothyroidism.ESR (35.5 ± 24.2 mm/h vs. 18.4 ± 5.0 mm/h) was significantly higher in patients RA. According to our research, 3.39% of the patients had low disease activity, 20.34% had moderate disease activity, and 76.27% had high disease activity. High disease activity positively correlated with the presence of thyroid gland pathology. Conclusion. The association between thyroid pathology and RA was confirmed, its presence correlated with high disease activity by DAS28-ESR. The routine screening for thyroid disorders in patients with rheumatoid arthritis is recommended for early diagnosis and correction of TG pathology in RA. |
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Cuvinte-cheie artrita reumatoidă, patologia glandei tiroide, boala autoimună, artrita reumatoidă, patologia glandei tiroide, boală autoimună |
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