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Articolul urmator |
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SM ISO690:2012 CAZACU, Janna, VATAMAN, Eleonora. The evolution of pulmonary hypertension early after coronary artery by-pass grafting in patients with heart failure. In: Cercetarea în biomedicină și sănătate: calitate, excelență și performanță, Ed. 1, 20-22 octombrie 2021, Chişinău. Chișinău, Republica Moldova: 2021, p. 106. ISBN 978-9975-82-223-7 (PDF).. |
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Cercetarea în biomedicină și sănătate: calitate, excelență și performanță 2021 | |||||
Conferința "Cercetarea în biomedicină și sănătate: calitate, excelență și performanță" 1, Chişinău, Moldova, 20-22 octombrie 2021 | |||||
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Pag. 106-106 | |||||
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Background. Pulmonary hypertension (PH) is a common complication of chronic heart failure (cHF), but its evolution in patients who are undergoing myocardial revascularization by coronary artery bypass grafting (CABG) remains unclear. Objective of the study. Determining the evolution of PH, estimated by echocardiography (EchoCG), in patients with different clinical phenotypes of HF after myocardial revascularization by CABG. Material and Methods. Prospective analytical study, which included 126 patients (mean age 62.23±8.5 years, 67.5% were men) with cHF and CABG, divided according to HF phenotype: HF with preserved ejection fraction (HFpEF), HFmid-range(mr)EF, HFreduced(r)EF, investigated through EchoCG in the preoperative and early postoperative stage. Statistical analysis: mean, frequencies, t-student test, ANOVA. Results. In the preoperative stage more than 50% of all patients had a low probability of PH. The mean pulmonary artery systolic pressure (PSAP) was higher in the HFrEF subgroup of patients (44.18±12.8 mmHg) in comparison with HFmrEF and HFpEF subgroups (41.42±11.6 mmHg and 36.43±11.4 mmHg), p<0.05. Early after cardiac surgery there was a reduction of mean value of PSAP in the general group of patients by 8.55±0.5mmHg, p<0.001 and the rate of cases with low probability of PH increased by 28,5%, p < 0.05. The higher mean PSAP at this stage (35.73±11.1 mmHg) was registered in the HFmrEF subgroup compared to those with HFrEF (33.93±7.5 mmHg) and HFpEF (28.87±8.6mmHg), p<0.01. Conclusion. Both before and after heart surgery EcoCG established a low probability of PH in most cases, with a higher percentage postoperatively (79.8% vs. 51.3%). PSAP is superior in patients with HFrEF preoperatively, but postoperatively it is higher in those with HFmrEF. |
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Cuvinte-cheie pulmonary hypertension, heart failure, coronary artery bypass grafting, hipertensiune pulmonara, insuficienţă cardiacă, by-pass coronarian |
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