Articolul precedent |
Articolul urmator |
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Ultima descărcare din IBN: 2024-03-01 10:30 |
SM ISO690:2012 ANDRONACHI, Nicoleta, PRISAKARI, Viorel I., BERDEU, Ion. The antimicrobial resistance profile of Acinetobacter strains. In: Cercetarea în biomedicină și sănătate: calitate, excelență și performanță, Ed. 1, 20-22 octombrie 2021, Chişinău. Chișinău, Republica Moldova: 2021, p. 90. ISBN 978-9975-82-223-7 (PDF).. |
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Cercetarea în biomedicină și sănătate: calitate, excelență și performanță 2021 | ||||||
Conferința "Cercetarea în biomedicină și sănătate: calitate, excelență și performanță" 1, Chişinău, Moldova, 20-22 octombrie 2021 | ||||||
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Rezumat | ||||||
Background. Acinetobacter is one of the main gram-negative nosocomial pathogens, multidrug resistant to currently available antimicrobial, including carbapenems, and in some regions even to colistin, being included in the group of critical microorganisms called ESKAPE. Objective of the study. To estimate the level of antibiotic resistance of Acinetobacter strains obtained from patients with nosocomial infections in multidisciplinary hospitals. Material and Methods. The cross-sectional descriptive epidemiological study was performed based on data collected from the records of microbiological laboratories, obtained in 2014-2018 in three multidisciplinary hospitals. The research group included 2140 strains of Acinetobacter isolated from patients with nosocomial infections. Statistical data were processed using IBM SPSS Statistics 20. Results. The strains of Acinetobacter showed a high resistance to most antibiotics (81.52%), while an increased sensitivity was found only to tetracyclines (63.04%) and polymyxins (95.83%). The multiannual dynamics showed a significant increase in resistance to cephalosporins with beta-lactamase inhibitors in 2018, compared to 2014 (30%→93.33%), to carbapenems (67.85%→80.65%), and tetracyclines (9.78%→81.07%). A. baumannii proved to be the most resistant (82.13%), followed by A. haemolyticus (56.67%), A. lwoffii (32.12%), while A. junii was sensitive (100%). Of the strains of Acinetobacter, 73.10% were carbapenem-resistant, and 98.06% of them were polyresistant to antibiotics. Conclusion. Acinetobacter strains showed a high level of resistance to antibiotics used in medical practice and represent an alarming issue, requiring a rational use of antibiotics to limit the formation and spread of multidrug resistant Acinetobacter strains |
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Cuvinte-cheie Acinetobacter, antimicrobial resistance, carbapenem resistant strains, Acinetobacter, Rezistenţă la antibiotice, tulpini carbapenem-rezistent |
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