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Articolul urmator |
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Ultima descărcare din IBN: 2023-04-16 23:54 |
SM ISO690:2012 GAMANIUC, Marina, VESELOVSKAIA, Ana, VIŞNEVSCHI, Anatolie. Association of pulmonary tuberculosis and COVID-19. In: Cercetarea în biomedicină și sănătate: calitate, excelență și performanță, Ed. 1, 20-22 octombrie 2021, Chişinău. Chișinău, Republica Moldova: 2021, p. 41. ISBN 978-9975-82-223-7 (PDF).. |
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Cercetarea în biomedicină și sănătate: calitate, excelență și performanță 2021 | ||||||
Conferința "Cercetarea în biomedicină și sănătate: calitate, excelență și performanță" 1, Chişinău, Moldova, 20-22 octombrie 2021 | ||||||
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Pag. 41-41 | ||||||
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Rezumat | ||||||
Background. The World Health Organization (WHO) estimated in 2019 10 million cases of tuberculosis (TB) with 1.6 million deaths worldwide. Since 2020, COVID-19 is a respiratory disease that has spread globally with approximately 111 million cases reported to the WHO. Objective of the study. Studying data from the literature on the interaction of pulmonary tuberculosis and COVID-19 Material and Methods. Data from the literature were analyzed using the PUBMED, Google academic and HINARI databases, referring to pulmonary tuberculosis, COVID-19, TB / COVID-19. Results. The results of the studies indicate that COVID-19 induces an adaptive immune response specific to the SARS-CoV-2 antigen involving CD4, CD8 cells and B lymphocytes. In particular, SARS-CoV-2-specific CD4 + T cells are associated with a protective immune response, while an insufficient immune response is associated with increased severity of the disease. COVID-19 is characterized by lymphopenia which is considered a marker of severe disease. Little evidence is currently available on co-infection with SARS-CoV-2 and Mycobacterium tuberculosis. TB could play a role in the development of COVID-19 infection and exacerbate the course of the disease for the co-infected population. Conclusion. Actually are insufficient studies on the impact of COVID-19 disease on tuberculosis. Because COVID-19 and TB disrupt the host's immune response, it can be assumed that their synergism contributes to a more severe clinical course. |
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Cuvinte-cheie pulmonary tuberculosis, COVID-19, TB / COVID-19, tuberculoză pulmonară, COVID-19, TBC/COVID-19 |
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