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SM ISO690:2012 ROTARI, Mihaela, GLOBA, Tatiana. The role of the type b natriuretic peptide test in the diagnosis and treatment of heart failure. In: Cercetarea în biomedicină și sănătate: calitate, excelență și performanță, Ed. 1, 20-22 octombrie 2021, Chişinău. Chișinău, Republica Moldova: 2021, p. 14. ISBN 978-9975-82-223-7 (PDF).. |
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Cercetarea în biomedicină și sănătate: calitate, excelență și performanță 2021 | ||||||
Conferința "Cercetarea în biomedicină și sănătate: calitate, excelență și performanță" 1, Chişinău, Moldova, 20-22 octombrie 2021 | ||||||
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Pag. 14-14 | ||||||
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Rezumat | ||||||
Background. B-type natriuretic peptide (BNP) is synthesized by ventricular cardiomyocytes due to overload volume. Serum levels of inactive NT-proBNP and the biologically active molecule BNP can be used to evaluate non-invasively ventricular pressure. Objective of the study. Assessment of the importance and relevance of the BNP test in the early diagnosis of heart failure (HF), staging the evolution of heart disease and monitoring the effectiveness of treatment. Material and Methods. The literature review was based on studies of patients with suspected heart failure. The relevance of cost-effectiveness and impact on treatment success were analyzed. The words used in the search engine were: BNP test, heart failure, heart failure diagnosis. Results. The upper limit of serum BNP is 100 pg / ml. According to Dilek Ural, BNP level <100 pg / ml and NT-proBNP level <300 are criteria for excluding suspected HF. During the treatment of HF, the decrease of serum BNP indices by 30-50% compared to the initial value are the indicators of a good prognosis in more than 70% of cases. C Balion states that the sensitivity of BNP and NT-proBNP tests is 92-97%, the specificity of 52-79%. Moreover, there was estimated a decrease of hospitalization, at least one day in patients undergoing GNP testing. Conclusion. As the level of BNP increases, so does the certainty of the diagnosis of heart failure and the severity of the condition. The use of this test has considerably reduced the time of diagnosis, stress of patients and caregivers |
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Cuvinte-cheie natriuretic peptide type B, heart failure, peptid natriuretic tip B, insuficienţă cardiacă |
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