The association of alcohol use with in hospital trauma deaths remain unclear. This study tries to identify the association of blood alcohol content with outcomes. Methods: Four electronic databases (MEDLINE, research4life, PubMed, ScienceDirect) were searched from 2015 to 2021 using a search strategy. The search strategy included a combination of medical subject headings (Mesh), and variations of keywords such: trauma, polytrauma, injury, alcohol, ethanol positive, blood alcohol level, and outcome. Some studies concluded that there is a better outcome for BAC positive patients. Results: A total of 17 studies were published between 2015 and 2021. In total, were included 558577 trauma patients in 17 studies, number of patients ranging from hundreds to tens of thousands. Studies varied in the mechanism of traumatic injury, injury-related to specific body areas, patient ages. Also, studies vary about the level of BAC+ (Blood Alcohol Content/concentration level). While other studies suggest an opposite opinion. It seems that data is more informative for TBI (Traumatic Brain Injury) where most studies related to a better outcome for trauma patients with BAC positive. Conclusion: Some studies present alcohol as a protective factor for trauma patients, while other studies present BAC as a worsening factor for patient outcome. No doubt that is necessary more studies in this direction.