Studied the effect of biologically active substances - an injectable preparation from plant tissues and means containing I and Se (amyloidin and Eselenium), on some parameters of boars sperm quality. The experimental group was specially selected animals at the age of 7-9 months with lower qualitative and quantitative indicators of sperm quality. In both groups, the animals were injected 4 times (once a week) with E-selenium at a dose of 1 ml / 50 kg. body weight. In the experimental group, were injected four times (once a week) 4 ml tissue preparation based on plant extract mixed with 2 ml. 0.5% novocaine, and once a day for 60 days, 150 mg of amyloidin was given with food. After the end of the experiment, the number of live sperm in the ejaculate of boars in the experimental group increased by 7.48%, and in the control group by 1.09%. In boars of the experimental group, the number of rectilinear-translational spermatozoa increased by 15.62%, and in the control group - by 12.82%.