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Ultima descărcare din IBN: 2024-02-22 17:16 |
SM ISO690:2012 EREMIA, Victor. Studiul comparativ al utilizării pericardului porcin decelularizat și a membranei Bioteck heart. In: Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”, 21-23 octombrie 2020, Chişinău. Chişinău: USMF, 2020, p. 615. |
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Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” 2020 | ||||||
Congresul "Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”" Chişinău, Moldova, 21-23 octombrie 2020 | ||||||
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Pag. 615-615 | ||||||
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Rezumat | ||||||
Background. Currently, the use of biological grafts is a promising option in the reconstruction of large diaphragmatic defects, in this context being proposed a lot of biological materials. Objective of the study. Comparative evaluation of radiological and morfopathological analysis of changes decellularised porcine pericardium and the diaphragm Bioteck Experimental Heart reconstruction of major defects diaphragmatic. Material and Methods. The study group included 6 pigs undergoing surgery with the creation of a defect about 5 cm in diameter. Decellularized grafts of porcine pericardium (group 1 - 3 animals) and Bioteck heart membrane (group 2 - 3 animals) were used in the reconstruction of the diaphragmatic defect. The animals were evaluated radiologically at 15, 30, 60 and 90 days postoperatively. At 90 they were sacrificed. Results. The radiological examination performed 15 days postoperatively established a normal configuration of the neohemidiaphragm created in both groups. At 60 days postoperatively, in group 1 the eventration of the neohemidiaphragm was documented, while in group 2 the normal configuration of the neohemidiaphragm was preserved until sacrifice. The data of the morphopathological investigations highlighted different aspects of regeneration and remodeling of these biological materials. Conclusion. Compared to the decellularized pig pericardial graft, the Bioteck Heart membrane showed a slower tissue degradation with an acceptable stability and cytocompatibility, being a promising alternative option in the reconstruction of diaphragmatic defects. |
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Cuvinte-cheie diaphragmatic defect, decellularized pericardium, defect diafragmatic, pericard decelularizat |
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