Articolul precedent |
Articolul urmator |
274 2 |
Ultima descărcare din IBN: 2021-11-07 10:28 |
SM ISO690:2012 PLEȘCA, Iulia, HADJIU, Svetlana. Eficiența cauză-tratament în crizele epileptice la nou-născut. In: Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”, 21-23 octombrie 2020, Chişinău. Chişinău: USMF, 2020, p. 557. |
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Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” 2020 | ||||||
Congresul "Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”" Chişinău, Moldova, 21-23 octombrie 2020 | ||||||
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Pag. 557-557 | ||||||
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Rezumat | ||||||
Background. Epileptic seizures (ES) represent one of the most frequent clinical manifestations in newborns, with a frequency of 1-5 cases in 1000 live births. The risk factors that can cause ES are different and correlate with the developing immature brain and underlying brain lesions. Objective of the study. Research of the causes that could lead to ES in newborns and analysis of the administered anti-epileptic medication, in order to appreciate the cause-treatment efficiency. Material and Method. Retrospective study based on the analysis of 24 medical records of full-term newborns, that had ES in the neonatal period. Investigation methods: cerebrospinal fluid analysis, neurosonography, computed tomography, magnetic resonance imaging, electroencephalography, metabolic tests. Results. Types of ES: Motor (62,5%): clonic (40%), automatisms (20%), myoclonic (13,4%), tonic (13,4%), epileptic spasms (6,6%), hyperkinetic (6,6%); Non-motor (29%): autonomic (57%), conservation of behavior (43%); Unclassified (8,5%). Causes, confirmed through additional investigations: anoxic and hypoxic-ischemic disorders (37,5%); neuroinfections (16,7%); intracranial hemorrhages (12,5%); metabolic disorders (8,3%); cerebral malformations (8,3%); ischemic strokes (4,2%); tuberous sclerosis (4,2%); unknown causes (8,3%). Administered treatment: diazepam (91,7%), remission of ES in 27,3% cases; phenobarbital (37,5%) – 55,5%; levetiracetam (29,2%) – 85,7% cases. Conclusion. Neonatal ES are atypical in comparance with other age groups and they relate to the preexisting brain lesions. The response to anti-epileptic drugs differs depending on the type of seizure and the cause. To identify ES, the research of their causes through additional investigations is needed. |
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Cuvinte-cheie epileptic seizures, newborn, cause, treatment, crize epileptice, nou-născut, cauză, Tratament |
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