Articolul precedent |
Articolul urmator |
518 2 |
Ultima descărcare din IBN: 2021-10-24 19:07 |
SM ISO690:2012 MATIUȚA, Alina, CERNAT, Mircea, MIŞIN, Igor, CERNAT, Victor, ANTOCI, Lilian. Tumorile gastrointestinale stromale gastrice gigante. In: Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”, 21-23 octombrie 2020, Chişinău. Chişinău: USMF, 2020, p. 425. |
EXPORT metadate: Google Scholar Crossref CERIF DataCite Dublin Core |
Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” 2020 | ||||||
Congresul "Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”" Chişinău, Moldova, 21-23 octombrie 2020 | ||||||
|
||||||
Pag. 425-425 | ||||||
|
||||||
Descarcă PDF | ||||||
Rezumat | ||||||
Background. Gastrointestinal stromal tumors (GIST) represent 0.1-3% of all mesenchymal neoplasms of the gastrointestinal tract and giant gastric (GG) GIST are rare. Objective of the study. Study of clinical, histopathological and immunohistochemical features and treatment results of GG GIST. Material and Methods. 92 patients with GG GIST(c-kit(CD117)(+) treated between 2007-2019. Study group–14 patients with GG GIST, M:F=1.8:1, mean age-59.78±2.35(95%CI:54.69-64.87) years. Results. Surgical options: excision of gastric tumor-2(14,3%), gastric wedge resection-7(50%), partial gastrectomy-5(35,7%). The mean maximum size of tumors 23,69±0,81(95%CI:21,93-25,44)cm. Immunohistochemical phenotype: CD117(+)–14(100%), CD34(+)–12(85.7%), desmin(+)–3(21.4%), vimentin(+)–10(71.4%), S-100(+)–3(21.4%), SMA(+)–8(57.1%), NSE–2(14.3%). Mean number of mitoses–24.36±6.3(95%CI:10.65-38.06). Tumors with high mitotic count were registered more frequent than with low mitotic count–11(78.6%) vs. 3(21.4%)(p<0.05). Metastases at first presentation– 28.6%(n=4) cases. Complex treatment – surgical and target therapy with imatinib mesylate–14(100%) patients. Conclusion. GG GIST are rare, but possess a higher risk of progression. Complex treatment is the best curative option. |
||||||
Cuvinte-cheie giant GIST, complex treatment, high risk, TGIS gigantă, tratament combinat, risc înalt |
||||||
|