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SM ISO690:2012 IURCIUC, Vladislav, HOTINEANU, Adrian, TARAN, Natalia, BERLIBA, Elina, TOACĂ, Inesa I.. Analiza scorurilor prognostice pentru estimarea supraviețuirii după transplant hepatic . In: Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”, 21-23 octombrie 2020, Chişinău. Chişinău: USMF, 2020, p. 418. |
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Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” 2020 | ||||||
Congresul "Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”" Chişinău, Moldova, 21-23 octombrie 2020 | ||||||
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Background. Despite recent advances in surgical techniques and medical management of patients, mortality after liver transplantation in the first year - 17%. In order to improve the results, it is necessary to adapt a prognostic score or create a score capable of accurately predicting survival. Objective of the study. Analysis of the ability of prognostic scores to predict short-term post-transplant survival in patients who received liver transplantation in the Republic of Moldova. Material and Methods. A retrospective cohort study was performed, analyzing data from 53 patients who received a liver transplant in 2013-2020. The MELD score and its modified variants (MELD-Na, iMELD, uMELD, UKELD) were used to analyze the 3-month post-transplant survival trends of the recipients using Kaplan-Meier curves. Results. The final group consisted of 53 patients with a mean age of 47.4 years. The most common indication for transplantation was cirrhosis due to HDV (49%). The survival rate at 3 months after transplantation was 83%. In the group of patients with values of MELD score higher than the cut-off, the survival was lower (73.9%) than in the group with lower values (90%), but no difference was observed between groups (p = 0.085). The most statistically significant results (p = 0.001) following the Kaplan-Meier analysis were observed in MELD-Na, the survival rate in the group with values of MELD-Na score higher than the cut-off - 57.1%, and in the group with lower values - 92.3%. Conclusion. The MELD score did not prove to be an effective tool in estimating survival at 3 months after liver transplantation, and of its modified variants the most statistically representative results were reported to MELD-Na |
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Cuvinte-cheie liver transplantation, prognostic score, survival, MELD-Na, transplant hepatic, scor prognostic, supravieţuire, MELD-Na |
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