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Articolul urmator |
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Ultima descărcare din IBN: 2023-04-13 20:41 |
SM ISO690:2012 MARTÎN, Cristina, TAGADIUC, Olga. Valoarea prognostică a D-dimerilor în infecția cu COVID-19. In: Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”, 21-23 octombrie 2020, Chişinău. Chişinău: USMF, 2020, p. 49. |
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Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” 2020 | ||||||
Congresul "Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”" Chişinău, Moldova, 21-23 octombrie 2020 | ||||||
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Rezumat | ||||||
Background. The infection with novel Coronavirus (COVID-19) represents a new form of infection, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Thrombotic complications are manifested paraclinically by thrombocytopenia, elevated D-Dimer and prolonged prothrombin time. Objective of the study. Was to apreciate the D-dimers value as an early and effective predictive marker to establish the severe form of COVID-19. Material and Methods. A descriptive review was made, based on the specialized literature from january-may 2020 period, using the MEDLINE, PubMed and Cochrane database. Relevant articles were selected using the following keywords „ SARS-CoV-2ˮ, „D-Dimersˮ and „Thrombosisˮ. Results. D-Dimers are fibrin degradation products, markers of endogenous fibrinolysis and important laboratory indicators of fibrinolysis and coagulation. Studies performed in COVID-19 had shown increased D-dimer levels in the severe forms of disease, with significant risk of disseminated intravascular coagulation (DIC) and poor outcome for the patients. Older age, higher SOFA score, elevated D-dimers, are associated with increased probability of fatal outcome. CID development and the increased mortality rate in patients with COVID-19, were correlated with Ddimers levels higher than 3000 μg/L. Conclusion. D-dimers are important and effective prognostic tool in SARS-CoV-2 infection, determining the management of Covid-19 patients. Elevated D-dimers levels are associated with an increased risk of severe disease and mortality. |
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Cuvinte-cheie SARS-CoV-2, D-Dimer, thrombosis, SARS-CoV-2, D-Dimeri, tromboză |
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