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SM ISO690:2012 BENDELIC, Anastasia, RAICA, Marius. Densitatea microvaselor în peretele venei safene mari la pacienții cu afecțiuni metabolice asociate. In: Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”, 21-23 octombrie 2020, Chişinău. Chişinău: USMF, 2020, p. 18. |
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Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” 2020 | ||||||
Congresul "Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”" Chişinău, Moldova, 21-23 octombrie 2020 | ||||||
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Background. The media of vessels is virtually avascular, oxygen and nutrients reach the media by diffusion. The vessels of the media appear mainly from the adventitia. Objective of the study. To investigate the density of vasa vasorum in the wall of great saphenous vein and to evaluate the influence of the atherosclerosis and diabetes mellitus on it. Material and Methods. Great saphenous vein specimens (n=9) were collected from the patients whose lower limbs were amputated: crush-syndrome (CS), atherosclerosis (ATS), atherosclerosis associated with diabetes mellitus (ATS+DM). The speciments were double immunostaining for CD34 and α-SMA. Results. Immunohistochemical quantification revealed deeper penetration of vasa vasorum in the tunica media in all evaluated cases. In case of the CS the vessels of the adventitia (165 vessels/mm2) prevailed numerically those of the media (140 vessels/mm2). In case of the ATS the values of the vascular density were marked both in the adventitia (246±101 vessels/mm2) and in the media (250±130 vessels/mm2). In case of the ATS+DM the vessel density of the media (323±104 vessels/mm2) exceeded numerically the density of the adventitia (173±29 vessels/mm2). Conclusion. The increased microvessel density of the great saphenous vein may be induced by stimuli other than vessel wall thickness, including atherosclerosis and diabetes mellitus. |
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Cuvinte-cheie Great saphenous vein, vasa vasorum, vena safena mare, vasa vasorum |
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