Articolul precedent |
Articolul urmator |
333 1 |
Ultima descărcare din IBN: 2022-07-27 22:39 |
SM ISO690:2012 VOLOȘCIUC, Irina, MUNTEANU, Oxana, RUSU, Doina. Caracteristicile exacerbatorului frecvent cu bronșiectazii nonfibroză chistică. In: Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”, 21-23 octombrie 2020, Chişinău. Chişinău: USMF, 2020, p. 271. |
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Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” 2020 | ||||||
Congresul "Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”" Chişinău, Moldova, 21-23 octombrie 2020 | ||||||
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Pag. 271-271 | ||||||
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Rezumat | ||||||
Background. In patients with non-cystic fibrosis bronchiectasis (NCFB), exacerbation rate influences significantly the severity of the disease. Objective of the study. Evaluation of clinico-paraclinical variables in patients with NCFB according to the frequency of exacerbations. Material and Methods. A cross-sectional study on 123 patients diagnosed with NCFB, period 2017-2018. Radiological mReiff score, Charlson comorbidity index, lung function, microbiological and clinical data were collected. Statistical analysis was performed using the SPSS 22 software program; Chi-square and Mann-Whitney U tests were performed. Results. In 68,3% of cases, at least 2 exacerbations during the last year were registered. Compared with those who had less than 2 exacerbations (31,7%), patients from this group had more severe lung function (FEV1 44,2±21,1% vs 66,5±27,8%, p<0,01; FVC 60,0±20,9% vs 75,7±25,2%, p=0,001; FEV1/FVC 62,7±17,6% vs 73,4±13,6%, p=0,001), a higher Charlson index (2,7±1,7 vs 1,9±1,8, p=0,011) and mMRC dyspnea score (3,0±0,9 vs 2,0±1,3, p<0,01), more reduced SaO2 (90,8±8,6% vs 93,3±5,8%, p=0,035). No statistically significant differences were found according to smoking status, age, BMI, mReiff score, presence of hemoptysis, colonization by pathogenic bacteria. Conclusion. Frequent exacerbators with NCFB had worse lung function, dyspnea, SaO2 and Charlson index. |
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Cuvinte-cheie non-cystic fibrosis bronchiectasis, exacerbations, bronșiectazii non-fibroză chistică, exacerbări |
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