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Articolul urmator |
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Ultima descărcare din IBN: 2022-05-26 20:31 |
SM ISO690:2012 CALARAŞ, Diana, RUSU, Doina, DAVID, Aliona, BOTNARU, Victor. Particularități ale funcției pulmonare la pacienții cu pneumopatii interstițiale difuze. In: Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”, 21-23 octombrie 2020, Chişinău. Chişinău: USMF, 2020, p. 193. |
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Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” 2020 | ||||||
Congresul "Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”" Chişinău, Moldova, 21-23 octombrie 2020 | ||||||
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Pag. 193-193 | ||||||
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Background. Interstitial lung diseases (ILD) represent a group of disorders that are generally thought to share a common pattern of physiologic abnormality, characterized by a restrictive ventilatory defect and reduced lung diffusing capacity (DLCO). Objective of the study. To find distinctive features of the pulmonary function tests results in different types of ILD. Material and Methods. 40 consecutive patients with ILD, admitted to IFP “Chiril Draganiuc”, Chisinau, during January 2019-February 2020, were included in a retrospective study. We divided the cohort in 5 subgroups: IPF patients – 8 cases, NSIP – 7, Hypersensitivity pneumonitis (HP) – 9, Sarcoidosis patients – 10, and 6 histiocytosis (Hx) cases. Clinical data and pulmonary function tests (PFT) were analyzed. Results. In the study cohort the majority were women (55%), non-smokers (75%), mean age 58.95 ±14.1 years. IPF and HP patients expressed significantly more dyspnea when compared to Sarcoidosis (p=0.01), or the Hx (p=0.025). PFT revealed normal or slightly deviated from normal means: FEV1 - 80.7±21.7, FVC - 78.4±21.5, RV127.5±42.1, TLC-88.8±22.3 and DLCO - 52.6±21.5. We found restriction in 75% of patients, and obstruction only in 7,5%. An air-trapping pattern was identified in 32,5% cases in the cohort. Patients with Hx had statistically more air-trapping than IPF (p˂0.001) and NSIP patients (p=0.002). This pattern has been identified in 1/3 HP patients and in 10% of sarcoidosis patients. Conclusion. PFT can help identifying individual features of different types of ILD being able to show even obstructive changes in a group of diseases thought to be strictly restrictive. |
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Cuvinte-cheie spirometry, obstruction, restriction, PID, spirometrie, obstructie, restricție |
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