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SM ISO690:2012 CABAC-POGOREVICI, Irina, MIHALACHE, Georgeta, OCHIŞOR, Viorica, COJUHARI, Inessa, REVENCO, Valeriu. Hemodinamica intrarenală în hipertensiunea arterială și insuficiența cardiacă cu fracția de ejecție păstrată. In: Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”, 21-23 octombrie 2020, Chişinău. Chişinău: USMF, 2020, p. 191. |
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Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” 2020 | ||||||
Congresul "Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”" Chişinău, Moldova, 21-23 octombrie 2020 | ||||||
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Pag. 191-191 | ||||||
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Rezumat | ||||||
Background. Traditional cardiovascular risk factors in the general population are usually correlated with the prognosis in patients with heart failure with preserved ejection fraction (HFpEF). Objective of the study. The aim of the present study was to assess the implications of intrarenal hemodynamics (IRH) in HFpEF. Material and Methods. The research included 60 patients with HFpEF aged 18-79 years, All subjects underwent physical examination, 24-hours ambulatory BP and electrocardiography monitoring, echocardiography, intrarenal Doppler ultrasound, obtaining the following IRH parameters: renal resistive index (RRI), renal pulsatile index (RPI), acceleration time (AT). Results. The analysis of BP values showed that 22% (13 pts) had stage I HTN, 48% (29 pts) - stage II HTN and 30% ( 18 pts) – stage III HTN, whereas the mean age of HTN onset was 40,55 ± 10,27 years, the mean HTN duration being of 9,57 ± 7,12 years, mean ejection fraction 56 ± 4,562%, mean NT-proBNP levels 654 ± 93 pg/ml. There was a positive association of only IRR with ambulatory 24 hours SBP (r = 0,359, p < 0,01), mean daytime SBP (r = 0,260, p<0,05) ambulatory PP (r = 0,266, p < 0,01), age (r = 0,253, p< 0,01), left ventricular mass (r = 0,459, p < 0,001) and relative wall thickness (r = 0,293 p<0,01). Conclusion. In addition to local renal vascular properties, the central hemodynamic factors significantly influence the IRH in HFpEF. IRH is the result of a complex interaction between renal and systemic vascular factors useful in assessment of a large spectrum of cardiovascular conditions. |
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Cuvinte-cheie intrarenal hemodynamics, heart failure, hemodinamica intrarenală, insuficienţă cardiacă |
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