Introduction. Positive thinking is an effective tool in the success of the medical act. Along with the performance against disease, positive thinking remains to be a huge potential, a solution generator. A substantial component in the development of an effective curative methodology through the involvement of positive thinking is the bioethical one.   Aim of the study. Revealing the socio-bioethical aspects in various diseases, as well as facilitating the medical act by applying the bioethical principles.   Materials and methods. Scientific research, native reference studies, normative basis, international reference publications, research and statistical data were used in the study. At the same time, the bioethical and sociological analysis was applied.   Results. The analysis of the cases of various pathologies, acquired or inborn, reveals the various and effective possibilities of managing the medical act by applying positive thinking. The optimizations obtained are due to the involvement of additional theoretical medical analyzes and the correlation of the medical act with the bioethical principles.   Conclusions. (1) Most of the pathologies recorded in different patient groups mainly require multilateral medication by applying different methods. (2) The medical act can be optimized by coordinating the actions of positive thinking, made on bioethical benchmarks. (3) Bioethics remains an important factor in mediating medication through various methods, including through the use of positive thinking.