The objective of this study was to evaluate the effect of foliage fertilizer Ecolit application on yield and quality of soybean. The foliage fertilizer Ecolit was applied in dose 1,5 l/ha and 3 l/ha at branching and blooming stages of plants. Experimental results demonstrated that the treatments with this product increased the concentration of photosynthetic pigments in leaves, especially chlorophyll a. Ecolit application in dose 3 l/ha gives 0,48t per hectare addition to the yield comparing to the control variant (1,91 t/ha). Generally, the highest yield (2,35 t/ha) was registered after use of Ecolit in dose 3,0 l/ha. The application of this fertilizer increased the content of nitrogen and quantities of nutrients consumed by grain yields. It is suggested that application of Ecolit could be biotechnology option to increase the productivity and quality of soybean.