Introduction. The diagnosis and treatment of postsurgical complications with the deduction of therapeutical algorithm are major requirements of portal hypertension surgery. Ai m of the study. To analyze the postsurgical evolution of chronic liver disease in operated pacients having liver cirrhosis. Materials and methods. A retrospective analyze has been performed on 39 patients with this disease, which previously had surgical t reatment: azygoportal devascularization + open splenectomy (29 pacients) and assisted laparascopic surgery (10 pacients). All pacients, among which 24 women (21.5%) and 15 men (38.4%) with average age of 34.1 years, with various viral etiology: hepatitis v iral B (33.3%), hepatitis viral B + hepatitis viral D (46.1 %), hepatitis viral C (20.5%); after the surgery followed syndromal hepatotropic treatment. Results. Monitorization and investigation of the study lot according to the proposed clinical protocol have allowed the early diagnosis of belated complications, as follows: esophageal varices of II nd and III rd degree (20.5%), variceal digestive haemorrhage (7.6%), ascites (7.6%), thrombosis of the portal vein (15.3%), abscess in the spleen loge (2.5%). O ver half of these patients needed frequent hospitalizations, postsurgical monitoring and endoscopic or surgical treatment (2.5%), when required, which reduced the risk of unwanted clinical outcome, marked by hepatic decompensation. Conclusions. 1. In the evolution of liver cirrhosis after azygoportal devascularization and splenectomy appeared particular features, which require evaluation, complex investigations and prophylactic/ curative treatment in order to avoid undesirable complications. 2. The develop ment of the reoccuring esophageal varices with hemorrhagic risk enforce “banding” and endoscopic monitorization. 3. The presence of thrombosis of the spleno portal venous spindle involves a complex antiplatelet treatment, mixt imagery monitoring (computer tomography, portal doppler ultrasonography).