Introduction. According to several authors, tricuspid valve pathologies is diagnosed in 19 40% of cases. As rule, primary tricuspid insufficiency is accompanied by congenital anomalies of heart or other valvular anatomical defects. Most often these diseases manifests, a s a consequence of pulmonary hypertension, congestive and right ventricular dilation, rheumatic or infectious diseases, heart trauma or involvement in the tumoral process. In the Republic of Moldova, rheumatic origin of valvulopathy, remain with a signific ant share and are the leading cause of surgical intervention in patients with valvulopathy. Tricuspid insufficiency appeared as a result of rheumatic damage in 15 30% of cases. Prevail tricuspid damage associated with mitral or aortic diseases. Aim of the study. Study of morbidity, evolution of the disease, methods of diagnosis of tricuspid insufficiency in adults. Evaluation of clinical manifestations of tricuspid insufficiency; Materials and methods. The study included a sample of 123 patients 57 men an d 66 women, aged from 24 to 95 years, during the 2014 2017 period, with tricuspid insufficiency with diverse degrees, pure and associated with other valvulopathy. Patients were presented with clinical signs of Heart Failure, hypertension. All patients were investigated by Doppler echocardiography and were discovered organic as well as functional valvular disorders with unique tricuspid insufficiency, and with tricuspid insufficiency associated with other valvulopathy. Results. The morbidity analysis by in r elation to the affected patients gender, we found that women make the disease 53.65%, compared with men, accounting for only 46.34%. According to etiology, with rheumatic valvular lesions etiology were 30.08%, bacterial endocarditis 8.13%, pulmonary valvul ar heart disease 9.75%, ischemic cause 22.76%, hypertension cause 10.56%, hypertrophic cause 1.62%, heart dilation cause 3.25%, and 13.82% of multiple associated causes. Patients with clinical signs of Heart Failure: functional class II NYHA 20.32%, III 76 .42%, IV 2.43%. Tricuspid insufficiency associated by rhythm and conduction disturbances are: chronic atrial fibrillation 66.66%, atrial flutter 6.5% and LBBB 6.5%, RBBB 4.06%. Echocardiographic Doppler investigation, show 9.75% with single tricuspid insufficiency and 90.24% with multiple valvular diseases. Conclusions. Tricuspid valve insufficiency is caused direct by alterations of valves, and indirectly secondary to left heart failure or both of them associated with diverse degrees.