Introduction. Borderline ovarian tumors (BOT) are malignant epithelial ovarian tumors with a very low incidence, therefore lacking sufficient clinical experience in diagnostics and treatment. Aim of the study. This study characterized the histology, clinical features, diagnostics and therapy of BOT including patients treated at the Department of Oncogynecology of the Nicolae Testemitanu State University of Medicine and Pharmacy of the Republic of Moldova. Materials and methods. In this retrospective study, patients with BOT treated between 2000 and 2016 were analyzed according to their histological and clinical reports. Results. A total of 45 patients were enrolled. The median age was 45.6(range=18-83) years. Distribution of histological subtypes was: serous in 31 patients (57.4 %) and mucinous in 14 patients (42.6%). All patients underwent surgery and 6 patients (14.8%) were treated according to actual therapy recommendations during the initial surgery. Six patients (14.8%) received adjuvant chemotherapy contrary to treatment recommendations. In the case of 30 patients (66.7%), the definitive histological result matched in 88.9%. During average follow-up of 30.3 months (range=0-115,5 months), 6 patients (14.8%) developed tumor recurrence after 9 and 29 months, respectively, two patients (3.7%) died of causes other than BOT. Conclusions. Our study critically demonstrated that until a few years ago, BOTs were not usually treated according to international therapy recommendations chemotherapy and surgery. The rate of tumor recurrence was very low.