The incidence of varicella specific and nonspecific complications among children
Închide
Articolul precedent
Articolul urmator
444 0
SM ISO690:2012
BOTNARI, Diana. The incidence of varicella specific and nonspecific complications among children. In: MedEspera: International Medical Congress for Students and Young Doctors, Ed. 7th edition, 3-5 mai 2018, Chişinău. Chisinau, Republic of Moldova: 2018, 7, pp. 64-65.
EXPORT metadate:
Google Scholar
Crossref
CERIF

DataCite
Dublin Core
MedEspera
7, 2018
Congresul "International Medical Congress for Students and Young Doctors"
7th edition, Chişinău, Moldova, 3-5 mai 2018

The incidence of varicella specific and nonspecific complications among children


Pag. 64-65

Botnari Diana
 
”Nicolae Testemițanu” State University of Medicine and Pharmacy
 
Disponibil în IBN: 2 noiembrie 2020


Rezumat

Introduction. Initial infection with Varicella Zoster Virus (VZV) results in chickenpox (varicella), a contagious rash illness typically occurring among children aged 1–10 years. VZV has the potential to cause disseminated infection in immune compromised individuals. There are two types of complications in varicella disease: bacterial suprainfections and neurological complications that are quite rare. Aim of the study. To evaluate the incidence, clinical manifestations and the outcomes of specific and nonspecific secondary complications among children with varicellaa. Materials and methods. This is a retrospective study on 81 patients aged between 6 months and 17 years with neurological complications and bacterial superinfections related to varicella, recorded between 2016 and 2017. Results. In 61 % of children, varicella occurred before the age of 3, with a peak incidence in winter (39%) and autumn (30%); 72% of children were hospitalized within 4 days. The most common form of varicella was the medium one (69%) and 31% of children had the severe form. Out of 81 patients that had chickenpox, 47% of them had complications. The most frequent varicella complications were: bacterial superinfection of skin caused by St. aureus and Streptococcus pyogenes (9.8%), bronchitis (6.17%), otitis media (4.9%), tonsillitis (6.17%). Only in 3.7% of children the central nervous system was affected (acute cerebellar ataxia). Clinical manifestations of varicella related neurological complication were: ataxia (3 cases), vomiting and headaches (3), fever and seizures (3), shivers (2) and dizziness with slurred speech (1). Concomitant diseases that influenced the evolution of varicella were: anemia (10%), allergic contact dermatitis (6%), toxic encephalopathy (20%) and intestinal dismicrobism (7%). The hospital physicians prescribed antibiotics in 71 % of cases (aminopenicillins, cephalosporin II-III g) and 60 % of patients used acyclovir therapy. Conclusions. The incidence of specific and non-specific secondary varicella complications in hospitalized patients was high (47%). The outcome of varicella complications was favorable in immunocompetent patients without apparent long-term sequelae. A decrease in the morbidity of varicella complications will be possible only if there’s appropriate vaccination coverage.

Cuvinte-cheie
varicella, bacterial superinfections, complications, children