Introduction. Stroke has a major socio economic impact on the population. The consequences of the disease are fatal in 20 35 of cases, and in 30 60 patients report permanent functional difficulties of the upper limb. Mirror therapy is a relatively new method pr oposed in the treatment of post stroke hemiparesis. It is based on the activity of mirror neurons in the neuroplasticity process. The objective of the study was to evaluate the efficacy of mirror therapy in patients with neurological motor deficiency of th e upper limb resulting from an ischemic or hemorrhagic stroke. Materials and methods. This study was prospective, controlled, and pilot. It included a pretest and a posttest. A total of 20 stroke patients were included: 10 in the experimental group ( an d 10 in the control group ( EG underwent conventional rehabilitation program 2 hours a day for 14 days mirror therapy 30 min/day, 14 days, and GC only conventional rehabilitation program 2 hours a day, 14 days. The Functional Independence Measure ( Fugl Meyer Assessment(FMA) were performed at the beginning and at the end of the study to compare changes in motor recovery and motor function after intervention. Results. The patients from the experimental group achieved significantly higher scores (p < for FIM and FMA than those from the control group. EG showed improvements of 2.6% in FIM testing, compared with 1.2% in CG. The same differences were found using other examinations: FMA arm score increase by 9.7% in EG, GC by 3%; FMA hand sc ore EG increase by 11%, CG by 2.5%; FMA total score EG increase by 11% and CG only by 2.8%. Conclusions. This pilot study proved the efficacy of mirror therapy on the patients with neurological motor deficiency. This technique is a useful tool in trea ting the post stroke hemiparesis by easiness of implementation, low cost and acceptability. For maximum effect, sessions of mirror therapy should last 30 minutes/day, 5 days a week, 4 weeks.