Introduction. Conversion disorder is a neurological syndrome involving multiple somatic symptoms occurring without an organic cause. Multiple sclerosis is a chronic, demyelinating central nervous system disease characterized by a high degree of di sability. Aim of the study. To determine whether patients with multiple sclerosis exhibit or have a predisposition to conversion disorders. Materials and methods. We evaluated successively 32 patients with Multiple Sclerosis for 6 months. They completed th e following questionnaires: Screening Scale, Nijmegen Vegetative Profile, BECK Depression Questionnaire, Dissociated Disorders DES, Anxiety Spielberger, Somatoform Reactions, and Family Status. Results. The studied group of the patients is non homogeneous in terms of gender: 22 females ( 10 males ( 23 52 years old, with an average of 38.4 years, primary progressive 53.13%, recurrent remissive 43.75%, secondary progressive 3.2%. Vegetative disorders manifest 70% men and 63.63% women, anxiety 70% men and 77.27% women, depression 50% men and 45.45% women, dissociation disorders 50% men and 54.54% women, conversion disorders 40 men and 45% women, sensory motor disorders, 40% men and 50% women. Conclusions. Patients with multiple sclerosis devel op multiple conversion disorders, especially sensory motor, with a non significant prevalence of female sex, with primary progressive disease evolution.