Background. Chagas disease (CD) (American trypanosomiasis) is generated by the protozoan parasite Trypanosoma cruzi (T.cruzi) and transmitted by the reduviid bug in Latin America. Approximately 8-12 million people are infected with T.cruzi in Central and South America. Estimates of the number of annual deaths are around 50,000, 60% being related to sudden cardiac death. Overall, 4.2% of Latin American individuals living in European countries are chronically infected with T.cruzi. Case report. We present the case of a young man of 29 years old, professional football player originating from Brazil. The patient was admitted for establishing the cause of the patient syncope developed during physical activity. The past medical history was without particularities. We evaluated the patient by basic ECG, echocardiography, and effort test – all without abnormalities. Holter ECG monitoring revealed multiple episodes of unstained ventricular tachycardia and several episodes of complete atrioventricular block – maximal pause 3.5 sec. We have also found frequent polymorphic ventricular extrasystole, disappearing during physical effort. Biochemical panel was without abnormalities. Heart MRI showed multiple regions of myocardial infiltration, and cardiosclerosis. The heart MRI image was typical for Chagas cardiomyopathy, considering the patient origin. Because of the absence of experience with CD in Republic of Moldova, we have sent the patient for serological evaluation in European cardiac centers. Given the concomitant episodes of complete atrioventricular block, we couldn’t prescribe any antiarrhythmic drug for the ventricular tachycardia. The patient was recommended to avoid any physical activity. For arrhythmia control we indicated implantation of device with pacemaker and ICD functions. Serological diagnosis of CD was thereafter confirmed. Patient got recommendation to return in Brazil to the national center for Chagas disease, because of their huge experience. In Brazil, during physical effort – playing football, patient suffered syncope and died, probably because of malignant ventricular arrhythmia. Conclusions. Heart diseases caused by different germs, atypical for Republic of Moldova or this part of the Europe, should be taken in consideration in all causes of unexplained heart functional or morphological abnormalities, especially in patients who are coming from other geographical regions or travelling abroad.