The response was studied of winter wheat seeds (Moldova 5 and Albidum 114 varieties) on treatment with solutions of Reglalg, thenatural plant growth regulator. The plants, obtained from the seeds treated with Reglalg, had lower epicotyls length and, as a consequence, their tillering node was formed more than 1.4 - 2.2 cm deeper in the soil. As result, the experimental plantstillering node and node roots were speeded in the soil with higher moisture, and in snowless winter the soil temperatures on the level of this node was by 3-6o C higher (in the summer, respectively, lower) than that in subjected to tillering nodes of the check plants. All these factors provided protection of plants against extreme environmental conditions. In 2013-2014, treatment of Moldova 5 seeds with the solution of Reglalg before sowing assured the harvest increase from 57.3 q/ha in checkplot to 65.8 q/ha, in the experimental plot.