The most important role of plant gene banks is to provide plant selection breeders with required collection material for creation of more productive and more resistant cultivars and hybrids. Also it is necessary to help ecologists to preserve critically endangered populations until they are reintroduced into their old natural habitats. Germplasm in gene banks is conversed to the state of suspended vegetal functions in order to have suitable combinations of alleles and rare alleles of species in future. Actually plant germplasm is a collection of parts of plants for vegetative propagation: seeds or pollen for conservation of genetic structure of population, and shoots for conservation of specific gene combinations of individual samples. Conservation of plant genetic diversity is also necessary for creation of landscapes by introduction of species adapted to changing environmental conditions. Plant genetic resources play certain role in assurance of sustainable agricultural development, sustainable food production and environmental protection. Therefore, there is an urgent need for conservation of plant genetic material. Value of old seeds stored for a long time in gene banks, sometimes under non-optimal conditions, often decreases because their germinability usually declines, mutability percent increases, resistance to abiotic and biotic environmental factor is lost, i.e. aging processes occur in such seeds. Seed aging negatively affect obtainment of genetically uniform material. Sometimes these are seeds of rare and protected species, they are not much left and they must be conserved if not for cultivation of fully functional plants then at least for obtainment of meristems for further microclonal propagation [1]. Therefore development of methods of increase of the old seed viability (after long-term storage) is a highly topical task in the context of work with plant genetic resources.  In recent times various chemical and physical methods are used for increase of seed viability after ex situ conservation. Chemical methods involve the use of microelements, vitamins, sugars, acids, gibberellic acid, kartolin, fusicoccin, lectin and other bioactive substances, including natural bioregulators and other chemical substances [2, 3]. Among physical methods electric and magnetic fields, gamma and laser irradiation are emphasized [4, 5]. Center for Plant Genetic Resources of the Academy of Sciences of Moldova conducts investigations on the study of some aspects of aging of crop plant seeds and special attention is paid to finding new perspective methods and procedures of enhancement of seed viability after their long-term storage in genebanks. Method of accelerated seed aging is applied intensively to various agricultural plants and allows to obtain the old seeds in sufficient amount for numerous experiments using chemical and physical factors.  For some years we have tested natural bioregulators from the group of steroid glycosides (moldstim, ecostim, sostim, hiasciamoside, sisimbrifolioside and etc.) as exogenous inductors of the old seed germination that can stimulate initial processes of seed metabolism and are non-toxic preparations [6,7]. Steroid glycosides are secondary metabolites and have polyfunctional spectrum of action (including antioxidant effect). Being accumulated in sufficient amounts they are valuable raw sources for bioactive compounds and are localized in cells or cell membranes. It was revealed that steroid glycosides can actively influence the rate of aging in plant cells by reparation of damaged structures. Depending on concentration and structure they can have stimulating or inhibiting effect on seeds [7, 8]. Experiments have been conducted on the influence of steroid glycosides on seeds of different agricultural plants (vegetables, leguminous crops, cereals, medicinal plants and etc.) after ex situ conservation. Certain bioregu lators and concentrations that stimulate or inhibit seed germination processes have been found for each plant species and optimal exposures to soaking have been identified [6,7,8]. Thus it has been demonstrated the possibility of application of steroid glycoside as exogenous inductors of the old seed germination under their storage in plant gene banks.  Recently, low electromagnetic fields of the millimeter range are widely applied in medicine, biology and plant cultivation [9,10,11]. This refers to principally new patterns of interaction of biological objects with electromagnetic fields that yet cannot be fully explained from currently accepted points of view. Frequency intervals (and also single frequencies) and amplitude intervals have been found where the effect is clearly registered (resonance effect), while outside these intervals the effect may be absent [5,9]. The majority of works on use of the millimeter waves are conducted in animals, human and microorganisms [4,9]. There are very few such investigations in plants and even fewer in seeds [10,11]. However they can make significant contribution to solution of the problem of application of millimeter waves to living objects both for scientific and applied use. Experiments of many years focused on the study of millimeter irradiation influence on seed germination processes after their long-term storage in plant gene banks allowed to obtain sufficient data confirming possibility to use this method for activation of initial metabolic processes in seeds in case of ex situ conservation [12,13,14].