Spontaneous Baroreflex Sensitivity: Sequence Method Estimate at Rest is Highly Correlated to Heart Rate Variability
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2020-03-12 12:45
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BERG, K.; WESSEL, Niels; GAPELYUK, A.; KRAEMER, Jan; KURTHS, K.. Spontaneous Baroreflex Sensitivity: Sequence Method Estimate at Rest is Highly Correlated to Heart Rate Variability. In: NANO-2019: Limits of Nanoscience and Nanotechnologies. 24-27 septembrie 2019, Chişinău. Chișinău, Republica Moldova: 2019, p. 49.
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NANO-2019: Limits of Nanoscience and Nanotechnologies 2019
Conferința "SPINTECH Summer school “S/F Hybrid Structures for Spintronics”"
2019, Chişinău, Moldova, 24-27 septembrie 2019

Spontaneous Baroreflex Sensitivity: Sequence Method Estimate at Rest is Highly Correlated to Heart Rate Variability


Pag. 49-49

Berg K.1, Wessel Niels2, Gapelyuk A.1, Kraemer Jan2, Kurths K.1
 
1 Necunoscută, Germania,
2 Humboldt University in Berlin
 
Disponibil în IBN: 23 ianuarie 2020


Rezumat

We evaluate information obtained by the sequence method estimate (SME) to quantify the baroreflex sensitivity and its redundancy compared to the short-term heart rate variability in case of resting state measurements. Therefore, we reanalyzed (n=1828) beat-to-beat time series of heart rate as well as systolic blood pressure which were recorded using similar protocols of supine resting state position. We found a high correlation between short-term heart rate variability (HRV) and the SME of baroreflex sensitivity which increased for adapted parameters and reached r = 0.89 (p < 0.001). This adaptation involved higher limits for changes in blood pressure and heart rate and implies an inability of traversing the full range of pressures to correctly quantify the gain of the baroreflex compared to, for example, a pharmacological intervention. Thus, for short measurements and under resting conditions short term HRV carries similar vagally mediated information as SME, however the latter has a potentially large bias as estimate for the baroreflex sensitivity. Future studies will show whether autonomic testing may allow a reliable, non-invasive and non-pharmacological driven quantification of the gain of the baroreflex.