In the Republic of Moldova, 57,1% of the population are live in rural areas [23]. Wells and springs in rural areas serve as the main sources of drinking water. Thus, the study carried out in the Poganesti village (Hancesti district) has shown that the main pollution sources in the locality are, especially animal and domestic waste, that have great impact under the quality of drinking water. The study has showed that 55% of the wells, as well as the surface water (small river from the locality) are polluted with nitrogen compounds. Mineralization and total water hardness of the studied wells exceed 4 -7 times sanitary standards norms and, at the same time surface water corresponds to class V of quality after hardness and nitrate concentration index.