The unique structural features of spirooxindoles together with the diverse biological activities have made them privileged structures in new drug discovery. According to a large number of publications, such spiro compounds have different biological properties [1]. Among them are activities against numerous viruses. Previously, we and other authors have reported about spiro compounds that can potentially be used as anti-HIV agents, or in veterinary medicine against Bovine Viral Diarrhoea Virus (BVDV) [2,3,4]. Nowadays, compound 1 is being tested for its ability to inhibit the action of the tobacco mosaic virus- TMV, tomato spotted wilt virus-TSWV and cucumber mosaic virus-CMV.formulaTSWV infects a variety of hosts, contributing to its global economic impact on crops. There are over a thousand of different hosts for TSWV. The host range of TSWV includes economically important crops like tomatoes and tobacco. TMV is known as one of the most stable viruses. It has a very wide survival range. As long as the surrounding temperature remains below approximately 40 degrees Celsius, TMV can sustain its stable form. The effect of the tested compoundsagainst TSWV is studied on the tomatoes of Emir variety. Studies on the effects of the same compounds against CMV are conducted on Rodnichok cucumbers. The effect of the preparations is also tested under conditions of artificial infection of the susceptible variety of tomatoes Elvira with the TMV under controlled conditions (in the climate chamber-POL-ECO-APARAT).
The unique structural features of spirooxindoles together with the diverse biological activities have made them privileged structures in new drug discovery. According to a large number of publications, such spiro compounds have different biological properties [1]. Among them are activities against numerous viruses. Previously, we and other authors have reported about spiro compounds that can potentially be used as anti-HIV agents, or in veterinary medicine against Bovine Viral Diarrhoea Virus (BVDV) [2,3,4]. Nowadays, compound 1 is being tested for its ability to inhibit the action of the tobacco mosaic virus- TMV, tomato spotted wilt virus-TSWV and cucumber mosaic virus-CMV.formulaTSWV infects a variety of hosts, contributing to its global economic impact on crops. There are over a thousand of different hosts for TSWV. The host range of TSWV includes economically important crops like tomatoes and tobacco. TMV is known as one of the most stable viruses. It has a very wide survival range. As long as the surrounding temperature remains below approximately 40 degrees Celsius, TMV can sustain its stable form. The effect of the tested compoundsagainst TSWV is studied on the tomatoes of Emir variety. Studies on the effects of the same compounds against CMV are conducted on Rodnichok cucumbers. The effect of the preparations is also tested under conditions of artificial infection of the susceptible variety of tomatoes Elvira with the TMV under controlled conditions (in the climate chamber-POL-ECO-APARAT).
The unique structural features of spirooxindoles together with the diverse biological activities have made them privileged structures in new drug discovery. According to a large number of publications, such spiro compounds have different biological properties [1]. Among them are activities against numerous viruses. Previously, we and other authors have reported about spiro compounds that can potentially be used as anti-HIV agents, or in veterinary medicine against Bovine Viral Diarrhoea Virus (BVDV) [2,3,4]. Nowadays, compound 1 is being tested for its ability to inhibit the action of the tobacco mosaic virus- TMV, tomato spotted wilt virus-TSWV and cucumber mosaic virus-CMV.formulaTSWV infects a variety of hosts, contributing to its global economic impact on crops. There are over a thousand of different hosts for TSWV. The host range of TSWV includes economically important crops like tomatoes and tobacco. TMV is known as one of the most stable viruses. It has a very wide survival range. As long as the surrounding temperature remains below approximately 40 degrees Celsius, TMV can sustain its stable form. The effect of the tested compoundsagainst TSWV is studied on the tomatoes of Emir variety. Studies on the effects of the same compounds against CMV are conducted on Rodnichok cucumbers. The effect of the preparations is also tested under conditions of artificial infection of the susceptible variety of tomatoes Elvira with the TMV under controlled conditions (in the climate chamber-POL-ECO-APARAT).
The unique structural features of spirooxindoles together with the diverse biological activities have made them privileged structures in new drug discovery. According to a large number of publications, such spiro compounds have different biological properties [1]. Among them are activities against numerous viruses. Previously, we and other authors have reported about spiro compounds that can potentially be used as anti-HIV agents, or in veterinary medicine against Bovine Viral Diarrhoea Virus (BVDV) [2,3,4]. Nowadays, compound 1 is being tested for its ability to inhibit the action of the tobacco mosaic virus- TMV, tomato spotted wilt virus-TSWV and cucumber mosaic virus-CMV.formulaTSWV infects a variety of hosts, contributing to its global economic impact on crops. There are over a thousand of different hosts for TSWV. The host range of TSWV includes economically important crops like tomatoes and tobacco. TMV is known as one of the most stable viruses. It has a very wide survival range. As long as the surrounding temperature remains below approximately 40 degrees Celsius, TMV can sustain its stable form. The effect of the tested compoundsagainst TSWV is studied on the tomatoes of Emir variety. Studies on the effects of the same compounds against CMV are conducted on Rodnichok cucumbers. The effect of the preparations is also tested under conditions of artificial infection of the susceptible variety of tomatoes Elvira with the TMV under controlled conditions (in the climate chamber-POL-ECO-APARAT).
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