The adequate complex therapy of infectious diseases continues to evolve constantly. Effective treatment of these patients requires an algorithm that would influence the adaptive and protective functions of the organism through improved immune response. Suppression induced by parasitic antigens lead to the inhibition, proliferation and suppression of suppressive T lymphocytes, so that the entire process is self-controlling, by overcoming specific suppression. The goal of this study: comparative analysis of immunomodulatory therapy in patients with toxocariasis associated with diseases of respiratory organs. The materials and methods. Immunity was investigated in 83 patients with respiratory pathology-associated toxocariasis. In the supernatant solution after the cultivation of lymphocytes is determined the level of glucose. The patients, according to the non-randomized allocation method, were divided into three groups: the first group - 33 patients: anti-parasitic treatment Eskazol and BioR; second group - 28 patients: antiparasitic treatment Eskazol and Polioxidoniu; third group - 22 patients: antiparasitic therapy Eskazol. Results and discussions. The number of lymphocytes in all groups examined prior to treatment was significantly higher than in healthy persons (p <0,001). After treatment, the number of lymphocytes in the first and second group of patients increased significantly (p<0,05), and in the third group (without immunocorretion) only a tendency of quench increased. All this suggests a more favorable progression of the disease in groups 1 and 2 compared to group 3. Due to the fact that the examined patients we determined a significant decrease in T lymphocytes (CD3) and the functional activity of T lymphocytes by blast transformation reaction with PHA, we wanted to analyze the metabolic parameters of the lymphocytes (see table). The use of glucose (CG) by the T lymphocytes in the supernatant in all patient groups before treatment was verily low (p<0,001) compared to healthy persons. After treatment, this index continued to verily increase only to the patients in the first group (p <0,001), the patients in the 2 and 3 group there was only a tendency to increase it. Significant inhibition of T lymphocytes metabolism was determined in all the groups investigated prior to treatment, after treatment the modified indices increased more pronounced in the first and second group of patients, but did not reach the norm. Conclusion. The use of specific antiparasitic therapy with immunocorrectors induces a positive dynamics of the pathological process, while the administration of only antiparasitic therapy does not provide a favorable evolution of the pathological picture. Significant inhibition of T lymphocyte metabolism has been determined in all investigated groups prior to treatment, after the treatment the modified indexes increased more pronounced in the first (BioR) and second group of patients (Polioxidoniu), but did not reach the norm.