Sugar beet crop is highly dependent on climatic conditions during the growing period, especially moisture and mineral nutrition are the most severe environmental factors affecting agricultural production and its quality. An important and yet unexploited opportunity to increase the productivity of agricultural crops is considered using physiologically active substances (FAS), that have a broad spectrum of action, combining FAS properties and nutrient effects, being active at low concentrations. This plant is especially sensitive to the insufficiency of trace elements, in particular, boron and cobalt. It has become an axiom the affirmation that some micronutrients, particularly iron, cobalt, boron, participate in carbon assimilation, respiration, and are components of into the enzymes responsible for the synthesis of chlorophyll pigments, and enhances the activity of dehydrogenases, nitrate reductase, and others. Currently, puts the problem of improving the application of compounds with trace elements at low concentrations for optimize productivity and accumulation of sugar in the roots, designed to prevent environmental pollution. Therefore amendments by physiologically active substances, that contain micronutrients, are beneficial for achieving optimal maximum sugar yield. The objective of this study was the assessment the effect of a new coordination compound [Co(DH)2(PP)2][BF4]·2H2O, named Cobamid, containing Co and B, on the productivity and yield of sugar beet plants. Cobamide [Co(DH)2(PP)2][BF4]·2H2O is a coordination compound of cobalt(III) and boron on the basis of dimethylglyoxime (DH2), and nicotinamide (PP) in the form of a tan crystalline solid, soluble in water, methanol and ethanol, insoluble in diethyl ether. The complex belongs to the class of cobalamins and can be considered as the simplest model of the active center of the molecule of vitamin B12. The nicotinamide from the composition of the coordination compound is a substance with a regulatory and energetic role which is widespread in all plant organisms. It is a functional part of pyridine nucleotides - oxidative equivalents (NAD+) in catabolic processes or reductants (NADP) in anabolic processes. The results of investigation showed a true acceleration of germination and growth of seedlings under the influence of the compounds, which indirectly demonstrates their effect on cells division and biosynthesis cytoplasm components. Major influence provides seed treatment with cobamid solution in a concentration of 0.001 and 0.0005%. In these variants has been an increase in mass accumulation of 154.5 and 90.9 percent higher compared to seedlings in the control variant. The seed and foliar area treatment caused the formation of assimilation apparatus with high cont of photosynthetic pigments. Betta vulgaris L. plants, which have been given physiological active substances with cobalt and boron are able to maintain the activity of metabolic processes at a higher level compared to control plants, which have the influence on plant productivity and quality of production. Treatment seeds and plants during vegetation period with cobamid assured of getting the sugar production by 18.4% more than the control plants. Therefore, plants treated with aqueous solutions of coordination compounds - cobamid ensures compared with control plants increase harvest, the sugar content in them, which results in increased production of sugar on unit area. It can be concluded that coordination compound of cobalt and boron are physiologically active substances and has a positive impact on the productivity and production quality of sugar beet plants.