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Articolul precedent |
Articolul urmator |
701 26 |
Ultima descărcare din IBN: 2023-10-21 13:34 |
SM ISO690:2012 CORCIOVĂ, Andreia, CIOBANU, Constantin. Determinarea spectrofotometrică a codeinei din comprimate.. In: Sănătate Publică, Economie şi Management în Medicină , 2014, nr. 6(57), pp. 31-33. ISSN 1729-8687. |
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Sănătate Publică, Economie şi Management în Medicină | ||||||
Numărul 6(57) / 2014 / ISSN 1729-8687 /ISSNe 2587-3873 | ||||||
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Pag. 31-33 | ||||||
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A spectrophotometric method for the determination of codeine phosphate in tablet dosage forms has been described, based on the codeine ability to form with bromphenol blue in acidic media, a complex extractible in chloroform. The absorbance of the formed ion-pair complex was monitored spectrophotometrically at 413 nm. The range of linearity for the obtained complex was found to be 0.1–0.5 mg/ml. The proposed method has been successfully applied for the determination of codeine in industrial pharmaceutical forms |
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Cuvinte-cheie codeine phosphate, bromphenol blue, ion-pair complex |
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