| Conţinutul numărului revistei |
| Articolul precedent |
| Articolul urmator |
 |
 973 0 |
 SM ISO690:2012CUZAN, Olesea, KOCHEM, Amelie, SIMAAN, Ariane Jalila, BERTAINA, Sylvain, FAURE, Bruno, VIVIANE, Robert, SHOVA, Sergiu, GIORGI, Michel, MAFFEI, Michel, REGLIER, Marius, ORIO, Maylis. Oxidative DNA Cleavage Promoted by a Phenoxyl-Radical Copper(II) Complex. In: European Journal of Inorganic Chemistry, 2016, nr. 36(2016), pp. 1575-1584. ISSN 1434-1948. DOI: https://doi.org/10.1002/ejic.201601001 |
| EXPORT metadate: Google Scholar Crossref CERIF DataCite Dublin Core |
  European Journal of Inorganic Chemistry |
|
| Numărul 36(2016) / 2016 / ISSN 1434-1948 /ISSNe 1099-0682 | |
|
|
| DOI:https://doi.org/10.1002/ejic.201601001 | |
| Pag. 1575-1584 | |
| Rezumat | |
Three neutral copper(II) complexes [Cu(L)2X] [X = none, N,N-dimethylformamide (DMF)0.5, N,N-dimethylacetamide (DMA)0.5 for 1, 2, and 3, respectively] containing benzotriazole–phenolate ligand HL [HL = 2-(2H-benzotriazol-2-yl)-4,6-di-tert-pentylphenol] have been synthesized and investigated with single-crystal X-ray diffraction, elemental analysis, and spectroscopic techniques [ESI-MS, IR, UV/Vis, electron paramagnetic resonance (EPR)]. The geometry of complex 1 is distorted square planar, while the isostructural complexes 2 and 3 are pentacoordinated. The redox properties of complex 1 were studied by cyclic voltammetry, and the corresponding one-electron oxidized species was generated and characterized by UV/Vis and EPR. Theoretical calculations were performed to support and rationalize the experimental data. Complex 1 was evaluated for its capability to perform veratryl alcohol oxidation and oxidative cleavage of DNA in DMF and DMSO in the presence of different agents (hydrogen peroxide, ascorbate, dithiothreitol). |
|
| Cuvinte-cheie copper, N, Radicals, Redox chemistry, DNA cleavage, O ligands |
|
|
|
|
|
