Conţinutul numărului revistei |
Articolul precedent |
Articolul urmator |
973 5 |
Ultima descărcare din IBN: 2022-09-14 13:51 |
Căutarea după subiecte similare conform CZU |
577.21:616.1 (1) |
Материальные основы жизни. Биохимия. Молекулярная биология. Биофизика (657) |
Патология сердечно-сосудистой системы. Сердечно-сосудистые заболевания (975) |
SM ISO690:2012 DUCA, Maria, PALII, Ina, GALEA-ABDUȘA, Daniela. Variabilitatea expresiei unor gene asociate cu patologiile cardiovasculare. In: Revista de Ştiinţă, Inovare, Cultură şi Artă „Akademos”, 2017, nr. 2(45), pp. 65-70. ISSN 1857-0461. |
EXPORT metadate: Google Scholar Crossref CERIF DataCite Dublin Core |
Revista de Ştiinţă, Inovare, Cultură şi Artă „Akademos” | |||||
Numărul 2(45) / 2017 / ISSN 1857-0461 /ISSNe 2587-3687 | |||||
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CZU: 577.21:616.1 | |||||
Pag. 65-70 | |||||
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Rezumat | |||||
The aim of the research was to evaluate the variability of expression level of 18 genes in healthy (children and adults) and with cardiovascular diseases (ischemic cardiopathy with/without atrial fibrillation, cardiomyopathy and congenital aortic stenosis) human subjects using the quantitative PCR technique. Based on the performed molecular study, a high level of gene expression was observed in the group of the subjects with disease and a significantly lower variation in the group of healthy subjects, which indicates that under normal conditions the expression of these genes is manifested within the limits of the reaction norm and the genetic potential enrolled in hereditary structures and highlights the cellular homeostasis of the body in relatively small variation ranges. These results are in line with literature data that supports patient detection and diagnosis programs based on gene expression profile. |
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Cuvinte-cheie variabilitate, Expresia genelor, stare de sănătate, stare de boală |
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