We studied the concentration of advanced glycation end products of AGEs in the blood of 80 children with primary glomerulonephritis (GN) with various clinical stages of the disease. In children with various forms of GN in the acute phase of the disease are registered a significant increase in the blood concentration of AGEs. In the acute phase of clinical manifestations in patients with steroid-sensitive nephrotic syndrome (NS), the level of AGEs trustworthy increases by 2.3 times, and in steroid-resistant (NR) by 1.6 times as compared to the control group. In remission the level of AGEs decreases in comparison with the initial level, and does not differ from it in the control group. Determination of AGEs in the blood concentration can be used to monitor the activity of the disease process in children with various variants GN, as well as to monitor the effectiveness of the therapeutic interventions.