Background: The health of the Moldovan population requires special attention, due to direct and indirect biological, environmental, behavioural and health factors. Material and methods: We studied population morbidity from the following localities: town Cupcini, village Bratuseni, village Ruseni (Edinet district); town Vadul lui Voda, town Cricova, village Condrita (municipality Chisinău); village Rosu, village Moscovei, village Huluboaia (Cahul district). Statistical data were taken from the statistical report No 12, for the period from 2012 to 2014. Results: Morbidity analysis showed that the overall prevalence of increased average values was recorded in the village Bratuseni, Edinet district – 16119.0±247.70/000. In town Vadul lui Voda, Cricova, village Condriţa (municipality Chisinau), overall prevalence values ranged within 6967.0±813.0 – 8721.3±375.90/000. Meanwhile, village Rosu, village Moscovei, village Huluboaia (Cahul district), mean values of overall prevalence were included within 2379.8±574.8 and 3219.8±152.70/000. Analysis of the general incidence emphasized that the community in the North recorded mean values within 1370.5±0.7 – 11162.4±190.40/000, localities in the center and south - 1877.8±246.3 – 3149.0±187.80/000 and respectively 899.3±95.0 – 1244.8±339.80/000. Conclusions: Population morbidity was growing during 2012-2014. Prevalence of diseases of the circulatory, digestive and urogenital systems was higher in central areas and the osteoarticular system diseases – in northern communities. The incidence of cardiovascular, urogenital and osteoarticular diseases was higher in cities from North, and digestive system diseases – in central areas.